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Effects of Stressful Life Events on Patients with Recurrent Ahthous Ulcer

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Abstract

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Recurrent aphthous ulcer(RAU) is the most frequent form of oral ulceration with a prevalence in the general population ranging between 5% and 60%. The peak age of onset is between 10 and 19 years of age, and it can persist into adulthood and throughout the patient"s lifespan, with no gender predilection. The disease is characterized clinically into three types: minor aphthous ulcer, major aphthous ulcer and herpeticform ulcers. The cause of RAU is unknown and thought to be multifactorial with many triggers or precipitating factors that include familial tendency or genetic predisposition, allergy, medications, hormones, stress or anxiety, and immunologic abnormalities. The need for consideration of psychological factors in the pathogenesis of oral disease has been increasingly acknowledged over the last decades and many studies have highlighted the psycho-social impact of oral conditions. In this study, we tried to evaluate the influence of emotional stress in RAU. There were thirty patients with a clinical diagnosis of RAU and other subjects who did not show any signs of systemic disorders include RAU. They are evaluated by using modified Holmes and Rahe"s Social Readjustment Rating Scale (SRRS). As a result, a significantly higher level of stress was found in the RAU patients than the control group. Therefore it can be concluded that psychological stressors play an important role in the RAU.

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Àç¹ß¼º ¾ÆÇÁŸ¼º ±¸³»±Ë¾ç; »çȸÀû ÀçÀûÀÀ ÆòÁ¤Ã´µµ(SRRS); ½ºÆ®·¹½º¼º »ýÈ°»ç°Ç
Recurrent aphthous ulcer; Social readjustment rating scale (SRRS); Stressful life events

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